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US Patent 10005734 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

Patent 10005734 was granted and assigned to FORMA Therapeutics on June, 2018 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors

Is a

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Patent attributes

Patent Applicant

FORMA Therapeutics

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Current Assignee

FORMA Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

David R. Lancia, Jr.0

Zhongguo Wang0

Ann-Marie Campbell0

Anna Ericsson0

Gary Gustafson0

Jian Lin0

Justin Andrew Caravella0

R. Bruce Diebold0

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Date of Patent

June 26, 2018

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Patent Application Number

148581740

Date Filed

September 18, 2015

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Patent Citations Received

US Patent 11497743 Treating patients harboring an isocitrate dehydrogenase 1 (IDH-1) mutation

US Patent 11498913 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US Patent 10550099 Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors

US Patent 10550098 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US Patent 10577329 Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

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US Patent 10807976 Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase inhibitors

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US Patent 10889567 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US Patent 11576906 Inhibiting mutant IDH-1

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Patent Primary Examiner

D Margaret M Seaman

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Patent abstract

The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula:

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