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US Patent RE39680 Substituted heterocycle fused gamma-carbolines

Patent RE39680 was granted and assigned to Bristol-Myers Squibb on June, 2007 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Bristol-Myers Squibb
Bristol-Myers Squibb
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
RE39680
Patent Inventor Names
David M. Zawrotny0
Albert J. Robichaud0
Parthasarathl Rajagopalan0
Simon Haydar0
Taekyu Lee0
Wei Deng0
Wenting Chen0
Christopher D. McClung0
...
Date of Patent
June 5, 2007
Patent Application Number
11356421
Date Filed
February 16, 2006
Patent Citations Received
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US Patent 12128043 Pharmaceutical capsules comprising lumateperone mono-tosylate
0
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US Patent 11680065 Pharmaceutical compositions comprising 4-(6Br,10aS)-3-methyl-2, 3, 6b, 9, 10, 10a-hexahydro-1H, 7H-pyrido[3′, 4′, 5] pyrolo[1,2,3-de] quinoxalin-8YL)-1-(4-fluorophenyl)-butane-1-one and methods of treating conditions of the central nervous system
0
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US Patent 11690842 Pharmaceutical capsule compositions comprising lumateperone mono-tosylate
0
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US Patent 11753419 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders
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US Patent 11773095 Organic compounds
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US Patent 11872223 Amorphous solid dispersions
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US Patent 11957791 Methods
0
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US Patent 11958852 Compounds and methods
0
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Patent Primary Examiner
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Bruck Kifle
Patent abstract

The present invention is directed to certain novel compounds represented by structural Formula (I)or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6a, R6b, R7, R8, R9, X, b, k, m, and n, and the dashed lines are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep disorders, sexual disorders, migraine, conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.

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