Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Darren H Wakefield0
David B Rozema0
David L Lewis0
Eric A Kitas0
Ingo Roehl0
Linda Valis0
Peter Mohr0
Philipp Hadwiger0
...
Date of Patent
October 24, 2017
0Patent Application Number
149723850
Date Filed
December 17, 2015
0Patent Citations Received
0
Patent Primary Examiner
Patent abstract
The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to cell in vivo. The pharmacokinetic modulator improve in vivo targeting compared to the targeting ligand alone. Targeting ligand-pharmacokinetic modulator targeting moiety targeted RNAi polynucleotides can be administered in vivo alone or together with co-targeted delivery polymers.
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