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US Patent 12024706 Modified oligonucleotides targeting SNPs

Patent 12024706 was granted and assigned to University of Massachusetts on July, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

University of Massachusetts

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Current Assignee

University of Massachusetts

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Anastasia Khvorova0

Edith Pfister0

Neil Aronin0

Faith Conroy0

Julia Alterman0

Ken Yamada0

Date of Patent

July 2, 2024

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Patent Application Number

169883910

Date Filed

August 7, 2020

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Patent Citations

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US Patent 8304530 Methods and compositions for enhancing the efficacy and specificity of RNA silencing

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US Patent 7250496 Bioinformatically detectable group of novel regulatory genes and uses thereof

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Patent Primary Examiner

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CPC Code

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Patent abstract

Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided.

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