Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dineli Wickramasinghe0
Shouhua Xiao0
Tobias Raum0
Zheng Pan0
Claudia Blumel0
Elisabeth Nahrwold0
Patrick Hoffmann0
Peter Kufer0
...
Date of Patent
September 19, 2017
Patent Application Number
14815861
Date Filed
July 31, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides a bispecific antibody construct comprising a first human binding domain which binds to human CDH19 on the surface of a target cell and a second binding domain which binds a human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising the polynucleotide and a host cell transformed or transfected with the polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of the antibody construct in the treatment of melanoma, and a kit comprising the antibody construct.
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