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US Patent 11884720 Antibody constructs for MSLN and CD3

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118847200
Patent Inventor Names
Tobias Raum0
Claudia Blümel0
Jonas Anlahr0
Peter Kufer0
Doris Rau0
Julie Bailis0
Patrick Hoffmann0
Elisabeth Nahrwold0
Date of Patent
January 30, 2024
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Patent Application Number
152254230
Date Filed
August 1, 2016
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Patent Citations
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US Patent 8911732 Anti-mesothelin antibodies and immunoconjugates
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US Patent 9034324 Anti-BCMA antibodies
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US Patent 9096672 Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof
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US Patent 9150664 Binding molecules for BCMA and CD3
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US Patent 9243058 BCMA antigen binding proteins
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US Patent 9340621 Binding molecules for BCMA and CD3
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US Patent 9567399 Antibodies and immunocytokines
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US Patent 9598500 Binding molecules for BCMA and CD3
0
...
Patent Primary Examiner
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Lynn A Bristol
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CPC Code
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C07K 16/28
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C07K 2317/31
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C07K 16/2809
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Patent abstract

The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human MSLN on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.

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