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US Patent 9701759 Heterodimeric proteins

Patent 9701759 was granted and assigned to Xencor on July, 2017 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Xencor
Xencor
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Current Assignee
Xencor
Xencor
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
97017590
Patent Inventor Names
Gregory L. Moore0
John R. Desjarlais0
Matthew J. Bernett0
Rumana Rashid0
Date of Patent
July 11, 2017
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Patent Application Number
141553440
Date Filed
January 14, 2014
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Patent Citations Received
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US Patent 11945869 PD-1 single domain antibodies and therapeutic compositions thereof
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US Patent 11866507 Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same
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US Patent 11891434 Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
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US Patent 11780908 Anti-dengue virus antibodies, polypeptides containing variant FC regions, and methods of use
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US Patent 11780912 Composition for prophylaxis or treatment of IL-8 related diseases
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US Patent 11891432 Anti-dengue virus antibodies having cross-reactivity to Zika virus and methods of use
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Patent Primary Examiner
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Sean Aeder
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Patent abstract

The invention provides heterodimeric antibodies comprising a first heavy chain comprising a first Fc domain and a single chain Fv region that binds a first antigen. The heterodimeric antibodies also comprise a second heavy chain comprising a second Fc domain, a first variable heavy chain and a first variable light chain, wherein the first and second Fc domains are different.

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