Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brendan P. Eckelman0
Katelyn M. Willis0
Quinn Deveraux0
Michael D. Kaplan0
John C. Timmer0
Date of Patent
January 9, 2024
0Patent Application Number
159511370
Date Filed
April 11, 2018
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The invention relates generally to multispecific polypeptides having constrained CD3 binding. In some embodiments, the multispecific polypeptides contain cleavable linkers that, when cleaved, results in dual effector functions. Also provided are methods of making and using these multispecific polypeptides in a variety of therapeutic, diagnostic and prophylactic indications.
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