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US Patent 9499514 Antiproliferative compounds and methods of use thereof

Patent 9499514 was granted and assigned to Celgene on November, 2016 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Celgene
Celgene
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Current Assignee
Celgene
Celgene
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
94995140
Patent Inventor Names
Brian E. Cathers0
Antonia Lopez-Girona0
Matthew Daniel Correa0
Michael Pourdehnad0
Raj Raheja0
Ehab M. Khalil0
George W. Muller0
Hon-Wah Man0
...
Date of Patent
November 22, 2016
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Patent Application Number
147958370
Date Filed
July 9, 2015
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Patent Citations Received
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US Patent 12090147 Combination therapy with 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
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US Patent 11883389 Formulations of 2-(4-chlorophenyl)-N-((2-(2,6- dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
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Patent Primary Examiner
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Kamal Saeed
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Patent abstract

Compounds of formula I for treating, preventing or managing cancer are disclosed. Also disclosed are methods of treating, preventing or managing cancer, such as leukemia, comprising administering the compounds. In certain embodiments, the method of treatment comprise administering a compound provided herein in combination with a second agent. Pharmaceutical compositions and single unit dosage forms comprising the compounds are also disclosed.

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