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US Patent 9340786 RNA interference in dermal and fibrotic indications

Patent 9340786 was granted and assigned to Rxi Pharmaceuticals Corporation on May, 2016 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Rxi Pharmaceuticals Corporation

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Dmitry Samarsky0

Anastasia Khvorova0

James Cardia0

Joanne Kamens0

Karen G. Bulock0

Lyn Libertine0

Pamela A. Pavco0

Tod M. Woolf0

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Date of Patent

May 17, 2016

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Patent Application Number

136367550

Date Filed

March 24, 2011

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Patent Citations Received

US Patent 11753638 Conjugated oligonucleotides

US Patent 11767527 Modified oligonucleotides targeting SNPs

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US Patent 12077755 Bioactive conjugates for oligonucleotide delivery

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US Patent 12024706 Modified oligonucleotides targeting SNPs

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US Patent 11702659 Optimized anti-FLT1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

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US Patent 11926828 Methods for treating aging and skin disorders using nucleic acids targeting TYR or MMP1

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Patent Primary Examiner

0

Patent abstract

The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and fibrotic applications.

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