Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zahra Shahrokh0
Jan Powell0
Jing Pan0
Lawrence Charnas0
Pericles Calias0
Richard Pfeifer0
Teresa Leah Wright0
Thomas McCauley0
Date of Patent
March 15, 2016
0Patent Application Number
131689610
Date Filed
June 25, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides an effective and less invasive approach for direct delivery of therapeutic agents to the central nervous system (CNS). In some embodiments, the present invention provides methods including a step of administering intrathecally to a subject suffering from or susceptible to a lysosomal storage disease associated with reduced level or activity of a lysosomal enzyme, a composition comprising a replacement enzyme for the lysosomal enzyme.
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