Patent 9181535 was granted and assigned to The Chinese University of Hong Kong Chorus on November, 2015 by the United States Patent and Trademark Office.
This application provides transcription activator-like effector nucleases (TALENs), polynucleotide sequences encoding the TALENs, expression cassettes for producing TALENs to target cleavage of nucleic acids, and methods of producing and using the TALENs.