Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Date of Patent
October 6, 2015
0Patent Application Number
138297800
Date Filed
March 14, 2013
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides, among other things, methods and compositions for production of recombinant I2S protein with improved potency and activity using cells co-express I2S and FGE protein. In some embodiments, cells according to the present invention are engineered to simultaneously over-express recombinant I2S and FGE proteins. Cells according to the invention are adaptable to various cell culture conditions. In some embodiments, cells of the present invention adaptable to a large-scale suspension serum-free culture.
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