Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dave Nichols0
Date of Patent
June 9, 2015
0Patent Application Number
138297060
Date Filed
March 14, 2013
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides, among other things, improved methods for purifying I2S protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant I2S protein can be purified from unprocessed biological materials, such as, I2S-containing cell culture medium, using a process involving as few as four chromatography columns.
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