US Patent 8980247 Parvovirus methods and compositions for killing neoplastic cells
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Patent abstract
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same.
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Patent Inventor Names
Craig M. Meyers0
Samina Alam0
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US Patent 08980247 Parvovirus methods and compositions for killing neoplastic cells US Patent 8980247 Parvovirus methods and compositions for killing neoplastic cells
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Patent Number
08980247
Patent Number
8980247
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US Patent 08980247 Parvovirus methods and compositions for killing neoplastic cells
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Is a
Patent jurisdiction
Patent number
08980247
Date of patent
March 17, 2015
Patent application number
13324484
Date Filed
December 13, 2011
Patent primary examiner
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