Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Craig M. Meyers0
Samina Alam0
Date of Patent
March 17, 2015
Patent Application Number
13324484
Date Filed
December 13, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same.
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