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US Patent 8664189 RNA interference in skin indications

Patent 8664189 was granted and assigned to Rxi Pharmaceuticals Corporation on March, 2014 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Rxi Pharmaceuticals Corporation

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

James Cardia0

Joanne Kamens0

Pamela A. Pavco0

Tod M. Woolf0

William Salomon0

Anastasia Khvorova0

Dmitry Samarsky0

Date of Patent

March 4, 2014

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Patent Application Number

131203150

Date Filed

September 22, 2009

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Patent Citations Received

US Patent 12077755 Bioactive conjugates for oligonucleotide delivery

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US Patent 11702659 Optimized anti-FLT1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

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US Patent 11753638 Conjugated oligonucleotides

US Patent 11767527 Modified oligonucleotides targeting SNPs

US Patent 11926828 Methods for treating aging and skin disorders using nucleic acids targeting TYR or MMP1

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US Patent 12024706 Modified oligonucleotides targeting SNPs

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Patent Primary Examiner

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Patent abstract

The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal applications.

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