Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tammy T Huang0
Mark W. Sleeman0
Douglas MacDonald0
Joel H. Martin0
Date of Patent
November 22, 2011
0Patent Application Number
126379420
Date Filed
December 15, 2009
0Patent Citations Received
Patent Primary Examiner
Patent abstract
An human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human proprotein convertase subtilisin/kexin type 9 (hPCSK9) characterized by the ability to reduce serum LDL cholesterol by 40-80% over a 24, 60 or 90 day period relative to predose levels, with little or no reduction in serum HDL cholesterol and/or with little or no measurable effect on liver function, as determined by ALT and AST measurements.
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