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US Patent 11970724 Serum-free cell culture medium

Patent 11970724 was granted and assigned to Regeneron Pharmaceuticals on April, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
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Current Assignee
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119707240
Patent Inventor Names
Shawn M. Lawrence0
Amy S. Johnson0
Shadia Abike Oshodi0
Date of Patent
April 30, 2024
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Patent Application Number
173703890
Date Filed
July 8, 2021
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Patent Citations
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US Patent 7279159 VEGF inhibitor polypeptides
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US Patent 7294484 Production of polypeptides
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US Patent 7303694 Liquid crystals with reduced toxicity and applications thereof
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US Patent 7429491 Restricted glucose feed for animal cell culture
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US Patent 7435553 Isolating cells expressing secreted proteins
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US Patent 7455988 Inducible eukaryotic expression system
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US Patent 7582298 High affinity antibodies to human IL-6 receptor
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US Patent 6924124 Feeding strategies for cell culture
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Patent Primary Examiner
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David W Berke-Schlessel
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CPC Code
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C12N 2510/02
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C12N 2511/00
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C12P 21/00
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C07K 16/18
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C12N 5/0031
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C12N 5/0037
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C12N 5/0043
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C12N 2500/32
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Patent abstract

The specification describes an improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Ornithine, or a combination of ornithine and putrescine can be added to serum-free media or chemically defined media to improve viable cell density, to reduce cell doubling time, and to increase the production of a protein of interest.

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