Patent 7935796 was granted and assigned to Lexicon Pharmaceuticals, Inc. on May, 2011 by the United States Patent and Trademark Office.
Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.