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US Patent 11866709 Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

Patent 11866709 was granted and assigned to Alnylam Pharmaceuticals on January, 2024 by the United States Patent and Trademark Office.

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Patent abstract

The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.

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