Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jeffrey H. Grubb0
William S. Sly0
Date of Patent
January 18, 2011
0Patent Application Number
117696930
Date Filed
June 27, 2007
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention is directed to chimeral fusion proteins having an IgG1 antibody Fc portion and a lysosomal storage enzyme, particularly a Fc-GUS fusion protein useful in treating Sly's disease in an embryo or fetus. The invention is also directed to methods of treating in born errors of metabolism, particularly Sly's disease, in a fetus by delivering to a pregnant mother a Fc-MPS emzyme fusion protein.
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