Patent 7798377 was granted and assigned to Roche on September, 2010 by the United States Patent and Trademark Office.
A device for dispensing a substance, including a receptacle for the product, a piston plug axially moveable in the receptacle, an output member associated with the device for causing the piston plug to move axially, and a connecting mechanism for detachably connecting the output member to the piston plug by axially displacement of the output member and the piston plug relative to each other, wherein, after being connected, the output member and piston plug may be separated by relative twisting.