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US Patent 7740846 Inhibitors of angiopoietin-like 4 protein, combinations, and their use

Patent 7740846 was granted and assigned to Genentech on June, 2010 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Genentech
Genentech
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
77408460
Patent Inventor Names
Napoleone Ferrara0
Hanspeter Gerber0
Xiao Huan Liang0
Date of Patent
June 22, 2010
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Patent Application Number
111852150
Date Filed
July 19, 2005
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Patent Citations Received
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US Patent 12064420 Tie-2 activators targeting the Schlemm's canal
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US Patent 11666558 Methods of treating intraocular pressure with activators of Tie-2
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Patent Primary Examiner
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Larry R. Helms
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Patent abstract

Modulators of angiopoietin-like 4 protein are provided along with methods for their use in the treatment of diseases and pathological conditions. Combinations of ANGPTL4 antagonists and other therapeutics, e.g., anti-cancer agents, and methods of their use in the treatment of mammals susceptible to or diagnosed with cancer, or with relapse tumor growth or relapse cancer cell growth are also provided.

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