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US Patent 11666558 Methods of treating intraocular pressure with activators of Tie-2

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Patent
Patent
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Patent attributes

Patent Applicant
EyePoint Pharmaceuticals
EyePoint Pharmaceuticals
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Current Assignee
EyePoint Pharmaceuticals
EyePoint Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116665580
Date of Patent
June 6, 2023
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Patent Application Number
171504300
Date Filed
January 15, 2021
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Patent Citations
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US Patent 7632862 Pharmaceutical compositions that modulate HPTPbeta activity
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US Patent 7740846 Inhibitors of angiopoietin-like 4 protein, combinations, and their use
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US Patent 7769575 Three dimensional coordinates of HPTPbeta
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US Patent 7795444 Human protein tyrosine phosphatase inhibitors and methods of use
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US Patent 8188125 Human protein tyrosine phosphatase inhibitors and methods of use
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US Patent 8258311 Human protein tyrosine phosphatase inhibitors and methods of use
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US Patent 8329916 Human protein tyrosine phosphatase inhibitors and method of use
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US Patent 8846685 Human protein tyrosine phosphatase inhibitors and methods of use
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...
Patent Primary Examiner
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James D. Anderson
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CPC Code
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A61K 31/426
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A61P 27/02
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A61P 27/06
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Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for eye conditions associated with angiogenesis, for example, intraocular pressure, ocular hypertension, and glaucoma.

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