Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dasari Muralidhara Reddy0
Rapolu Raji Reddy0
Kura Rathnakar Reddy0
Bandi Parthasaradhi Reddy0
Kesireddy Subash Chander Reddy0
Date of Patent
March 30, 2010
Patent Application Number
11718359
Date Filed
November 25, 2005
Patent Primary Examiner
Patent abstract
The present invention provides an improved and commercially viable process for the preparation of oseltamivir phosphate. Thus, for example, ethyl (3R,4R,5S)-4-amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate is acetylated with acetic anhydride in methylene chloride in the presence of triethyl amine in the absence of water to give ethyl (3R,4R,5S)-4-(acetylamino)-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate.
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