Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Charlotte Albaek Thrue0
Daniel Sejer Pedersen0
Henrik Frydenlund Hansen0
Majken Westergaard0
Miriam Frieden0
Nikolaj Dam Mikkelsen0
Signe M. Christensen0
Troels Koch0
...
Date of Patent
March 30, 2010
0Patent Application Number
107174340
Date Filed
November 18, 2003
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to novel oligonucleotides with improved antisense properties. The novel oligonucleotides comprise at least one Locked Nucleic Acid (LNA) selected from beta-D-thio/amino-LNA or alpha-L-oxy/thio/amino-LNA. The oligonucleotides comprising LNA may also include DNA and/or RNA nucleotides. The present invention also provides a new class of pharmaceuticals which comprise antisense oligonucleotides and are useful in antisense therapy.
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