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US Patent 11788089 Compositions and methods for modulating MECP2 expression

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Contents

Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11788089
Patent Inventor Names
Arthur M. Krieg
Romesh R. Subramanian
James McSwiggen
Jeannie T. Lee
Date of Patent
October 17, 2023
Patent Application Number
16876271
Date Filed
May 18, 2020
Patent Citations
‌
US Patent 7683036 Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
‌
US Patent 8361980 Pharmaceutical compositions for treatment of microRNA related diseases
‌
US Patent 8404659 Pharmaceutical compositions for treatment of MicroRNA related diseases
‌
US Patent 8415313 Antisense oligomers and methods for inducing immune tolerance and immunosuppression
‌
US Patent 8846639 Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity
‌
US Patent 9328346 Polycomb-associated non-coding RNAs
‌
US Patent 9567581 Selective reactivation of genes on the inactive X chromosome
‌
US Patent 9580708 Multimeric oligonucleotides compounds
...
Patent Primary Examiner
‌
Amy H Bowman
CPC Code
‌
C12N 15/113
Patent abstract

Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of MECP2. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of MECP2. Methods for modulating expression of MECP2 using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of MECP2.

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