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US Patent 7572631 Activation and expansion of T cells

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
75726310
Patent Inventor Names
Stewart Craig0
Zahbea Saund0
Alan Hardwick0
Che Law0
Dale Kalamasz0
David McMillen0
Harjinder Singh Chana0
Mark Bonyhadi0
...
Date of Patent
August 11, 2009
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Patent Application Number
110708410
Date Filed
March 2, 2005
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Patent Citations Received
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US Patent 12121541 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 11963966 Compositions and methods for treating ovarian tumors
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US Patent 11965012 Compositions and methods for TCR reprogramming using fusion proteins
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US Patent 11981922 Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
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US Patent 11981921 TIL expansion processes using specific cytokine combinations and/or AKTi treatment
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US Patent 11994512 Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
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US Patent 11998568 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 12011480 Nanoparticle compositions for sustained therapy
0
...
Patent Primary Examiner
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L. Blaine Lankford
0
Patent abstract

The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.

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