Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
January 27, 2009
Patent Application Number
10947812
Date Filed
September 22, 2004
Patent Citations Received
Patent Primary Examiner
Patent abstract
Liver cancer, particularly hepatocellular carcinoma specific promoter sequences and adenovirus vehicles are provided. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity, for treating neoplasia.
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