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US Patent 7365166 Anti-VEGF antibodies

Patent 7365166 was granted and assigned to Genentech on April, 2008 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Genentech
Genentech
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
73651660
Patent Inventor Names
Henry B. Lowman0
James A. Wells0
Leonard G. Presta0
Manuel Baca0
Yvonne Man-Yee Chen0
Date of Patent
April 29, 2008
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Patent Application Number
115366030
Date Filed
September 28, 2006
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Patent Citations Received
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US Patent 12071476 IL-6 antibodies and fusion constructs and conjugates thereof
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US Patent 12121586 Optimized variants of anti-VEGF antibodies
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US Patent 11851493 Trispecific antagonists
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US Patent 11912784 Methods of treating an eye disorder
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US Patent 11945873 Antitumor antagonists
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US Patent 12016875 Methods for treating or preventing ophthalmological conditions
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US Patent 12018073 Antagonists targeting the TGF-β pathway
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US Patent 12077783 AAV-mediated delivery of antibodies to the inner ear
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...
Patent Primary Examiner
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David J Blanchard
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Patent abstract

Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.

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