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US Patent 11851493 Trispecific antagonists

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jackie Sheng0

Bo Liu0

Date of Patent

December 26, 2023

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Patent Application Number

169954140

Date Filed

August 17, 2020

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Patent Citations

US Patent 8992913 Antagonist antibodies against GDF-8 and uses therefor

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US Patent 9890204 Trivalent, bispecific antibodies

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US Patent 9987500 Human antibodies to PD-1

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US Patent 9994632 Humanized or affinity-matured anti Ang-2 antibody and uses thereof

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US Patent 10112997 Tight-binding agents and uses thereof

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US Patent 10189902 Antibodies to TIGIT

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US Patent 6884879 Anti-VEGF antibodies

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US Patent 7025962 Mammalian cell surface antigens; related reagents

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...

Patent Primary Examiner

Meera Natarajan

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Patent abstract

Antitumor antagonists that bind specifically to immune checkpoint regulator and/or components of the angiogenesis pathways and/or components of the TGF pathway are disclosed. Also disclosed is a method of treating proliferative disorders with the antitumor antagonists.

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