Patent 7253333 was granted and assigned to National Institute of Advanced Industrial Science and Technology on August, 2007 by the United States Patent and Trademark Office.
Provided is a special Drosophila strain having a Bradeion gene artificially incorporated therein to exclusively express the gene in the compound eyes and thus to exhibit rough eye. The Drosophila strain has the following properties:(a) a human-derived Bradeion gene has been transferred in the strain to express the human-derived protein Bradeion in the compound eyes from the developmental period;(b) the compound eyes show morphological abnormality due to the expression of Bradeion; and(c) the morphological abnormality occurring in the compound eyes is multiplied according to the number of transferred Bradeion genes.