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US Patent 7223741 Immunostimulatory nucleic acid molecules

Patent 7223741 was granted and assigned to University of Iowa on May, 2007 by the United States Patent and Trademark Office.

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Patent
Patent
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Current Assignee
University of Iowa
University of Iowa
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
72237410
Patent Inventor Names
Arthur M. Krieg0
Date of Patent
May 29, 2007
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Patent Application Number
106192790
Date Filed
July 14, 2003
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Patent Citations Received
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US Patent 11957788 Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
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US Patent 11696954 Synthesis of spherical nucleic acids using lipophilic moieties
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Patent Primary Examiner
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Janet L. Epps-Ford
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Patent abstract

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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