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US Patent 11696954 Synthesis of spherical nucleic acids using lipophilic moieties

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Patent
Patent
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Patent attributes

Patent Applicant
Exicure
Exicure
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Current Assignee
Exicure
Exicure
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116969540
Date of Patent
July 11, 2023
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Patent Application Number
166086850
Date Filed
April 27, 2018
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Patent Citations
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US Patent 7223741 Immunostimulatory nucleic acid molecules
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US Patent 7255868 Chimeric immunomodulatory compounds and methods of using the same—I
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US Patent 7256264 Receptor for IL-17 homologous polypeptides and uses thereof
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US Patent 7276489 Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
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US Patent 7332586 Nanoparticle delivery vehicle
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US Patent 7404969 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
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US Patent 7427405 Immunostimulatory oligonucleotide multimers
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US Patent 7470674 Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
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...
Patent Primary Examiner
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Isaac Shomer
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CPC Code
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A61K 9/127
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A61K 47/549
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Spherical nucleic acids (SNA) carrying self-aggregating oligonucleotides are described herein. Compositions of the SNA include discrete nanostructures that are not aggregated. Related methods are also described.

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