US Patent 7192729 Methods for assaying homocysteine

Patent 7192729 was granted and assigned to General Atomics on March, 2007 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

General Atomics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

71927290

Patent Inventor Names

Chong-Sheng Yuan0

Date of Patent

March 20, 2007

Patent Application Number

100437870

Date Filed

January 10, 2002

Patent Primary Examiner

‌

Rebecca E. Prouty

Patent abstract

The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or adenosine. More particularly, assay methods that employ, mutant SAH hydrolase having binding affinity for Hcy, SAH or adenosine but has attenuated catalytic activity, are provided. The modified enzymes and fusion proteins containing the modified enzymes are also provided.