Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christopher P. Prior0
Date of Patent
February 13, 2007
0Patent Application Number
103780940
Date Filed
March 4, 2003
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention discloses fusion proteins comprising transferrin, lactoferrin or melanotransferrin fused to glucagon-like peptide 1 (GLP-1). In one embodiment of the invention, the fusion protein displays increased serum half-life as compared to a GLP-1 peptide in an unfused state. The invention includes a pharmaceutical composition comprising the GLP-1 fusion protein of the invention and a carrier. The fusion protein of the invention can be administered to a subject for treatment of diseases or conditions treatable by GLP-1, including, but not limited to, diabetes, obesity, congestive heart failure and inflammatory bowel syndrome.
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