US Patent 7122207 High drug load acid labile pharmaceutical composition

Patent 7122207 was granted and assigned to Bristol-Myers Squibb on October, 2006 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Bristol-Myers Squibb

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

71222070

Date of Patent

October 17, 2006

Patent Application Number

098484480

Date Filed

May 3, 2001

Patent Primary Examiner

‌

S. Tran

Patent abstract

A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a disintegrant, and about 0% to about 10% by weight of a binder selected from the group consisting of sodium carboxymethylcellulose, hydroxypropylmethylcellulose, potassium alginate, and partially pregelatinized corn starch. A high drug load pharmaceutical composition, comprising the beadlet, with an enteric coating disposed thereon, is also provided.