US Patent 7078030 Oncolytic adenovirus
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Patent abstract
Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.
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Patent Inventor Names
Ali Fattaey0
Jerry Yuqiao Shen0
Leisa Johnson0
Sylvie Laquerre0
Terry Hermiston0
Date of Patent
July 18, 2006
0Patent Application Number
107336740
Date Filed
December 11, 2003
0Patent Primary Examiner
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US Patent 7078030 Oncolytic adenovirus
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