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US Patent 6858412 Direct multiplex characterization of genomic DNA

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Is a
Patent
Patent
0

Patent attributes

Patent Applicant
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
68584120
Patent Inventor Names
Maneesh Jain0
Mostafa Ronaghi0
Paul Hardenbol0
Ronald W. Davis0
Thomas D. Willis0
Viktor Stolc0
Date of Patent
February 22, 2005
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Patent Application Number
099993620
Date Filed
October 24, 2001
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Patent Citations Received
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US Patent 12129514 Methods and compositions for evaluating genetic markers
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US Patent 12077822 Methods for determining carrier status
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US Patent 12084720 Assessing graft suitability for transplantation
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US Patent 12084712 Sample indexing for single cells
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US Patent 12094573 Methods for multi-resolution analysis of cell-free nucleic acids
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US Patent 12104211 Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
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US Patent 12110537 Capture reactions
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US Patent 12110552 Methods for simultaneous amplification of target loci
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...
Patent Primary Examiner
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Jeffrey Fredman
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Patent abstract

The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified.

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