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US Patent 12129514 Methods and compositions for evaluating genetic markers

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Gregory J. Porreca0

Mark Umbarger0

Date of Patent

October 29, 2024

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Patent Application Number

139340930

Date Filed

July 2, 2013

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Patent Citations

US Patent 8529744 Enrichment of nucleic acid targets

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US Patent 10066259 Screening for structural variants

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US Patent 10202637 Methods for analyzing nucleic acid

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US Patent 10227635 Capture reactions

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US Patent 10604799 Sequence assembly

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US Patent 10683533 Capture reactions

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US Patent 6858412 Direct multiplex characterization of genomic DNA

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US Patent 6911345 Methods and apparatus for analyzing polynucleotide sequences

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Patent Primary Examiner

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Patent abstract

Aspects of the invention relates to methods and compositions that are useful to reduce bias and increase the reproducibility of multiplex analysis of genetic loci. In some configurations, predetermined preparative steps and/or nucleic acid sequence analysis techniques are used in multiplex analyses for a plurality of genetic loci in a plurality of samples.

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