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US Patent 12129309 Heterodimeric antibodies that bind CD3 and CD38

Patent 12129309 was granted and assigned to Xencor on October, 2024 by the United States Patent and Trademark Office.

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 US Patent 12129309 Heterodimeric antibodies that bind CD3 and CD38

Article

Patent abstract

The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Xencor
Xencor
0
Current Assignee
Xencor
Xencor
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
121293090
Patent Inventor Names
Gregory Moore0
John Desjarlais0
Matthew Bernett0
Rumana Rashid0
Seung Chu0
Umesh Muchhal0
Date of Patent
October 29, 2024
0
Patent Application Number
177364750
Date Filed
May 4, 2022
0
Patent Citations
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US Patent 7087600 Peptidyl prodrugs and linkers and stabilizers useful therefor
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US Patent 7112324 CD 19×CD3 specific polypeptides and uses thereof
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US Patent 7129261 Cytotoxic agents
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US Patent 7276497 Cytotoxic agents comprising new maytansinoids
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US Patent 7303749 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
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US Patent 7368565 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
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US Patent 7498302 Disulfide prodrugs and linkers and stabilizers useful therefor
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US Patent 7507420 Peptidyl prodrugs and linkers and stabilizers useful therefor
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US Patent 7517903 Cytotoxic compounds and conjugates
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US Patent 7601354 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
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US Patent 7642228 Method for making heteromultimeric polypeptides
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US Patent 7691962 Chemical linkers and conjugates thereof
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US Patent 7695936 Knobs and holes heteromeric polypeptides
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US Patent 7696338 Immunotoxin fusion proteins and means for expression thereof
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US Patent 7728114 Anti-CD3 antibodies and methods of use thereof
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US Patent 7850962 Human monoclonal antibodies against CD20
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US Patent 8063187 Methods and compositions for inhibiting CD32B expressing cells
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US Patent 8114967 Constructs and libraries comprising antibody surrogate light chain sequences
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US Patent 8216805 Knobs and holes heteromeric polypeptides
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US Patent 8236308 Composition comprising cross-species-specific antibodies and uses thereof
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US Patent 8309690 Integrated approach for generating multidomain protein therapeutics
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US Patent 8367805 Fc variants with altered binding to FcRn
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US Patent 8409568 Mutant antibody Fc domains and fusion proteins thereof
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US Patent 8592562 Method for making antibody Fc-heterodimeric molecules using electrostatic steering effects
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US Patent 8637641 Antibodies with modified isoelectric points
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US Patent 8946387 FcγRIIB specific antibodies and methods of use thereof
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US Patent 9181334 Pharmaceutical composition for treatment and/or prophylaxis of cancer
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US Patent 9822181 Bi-specific monovalent diabodies that are capable of binding CD123 and CD3, and uses thereof
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US Patent 9856327 Heterodimeric antibodies to CD3 X CD123
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US Patent 11225521 Heterodimeric antibodies that bind somatostatin receptor 2
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US Patent 11225528 Heterodimeric antibodies that bind CD3 and tumor antigens
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US Patent 10227410 Heterodimeric antibodies that bind CD3 and PSMA
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US Patent 10259887 Heterodimeric antibodies that bind CD3 and tumor antigens
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US Patent 10316088 Heterodimeric antibodies that bind somatostatin receptor 2
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US Patent 10294300 Antibody constructs for DLL3 and CD3
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US Patent 10428155 Trispecific antibodies
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US Patent 10526417 Heterodimeric antibodies that bind CD3 and CD38
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US Patent 11066483 Cytotoxicity-inducing therapeutic agent
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US Patent 11591401 Anti-CD28 compositions
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US Patent 6884869 Pentapeptide compounds and uses related thereto
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US Patent 6989452 Disulfide prodrugs and linkers and stabilizers useful therefor
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Patent Primary Examiner
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Sean E Aeder
0
CPC Code
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C07K 16/40
0

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