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US Patent 12122811 BDNF mimetic peptide amphiphiles

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 US Patent 12122811 BDNF mimetic peptide amphiphiles

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Patent abstract

Provided herein are peptide amphiphiles (PAs) and supramolecular PA nanostructures that mimic brain derived neurotrophic factor (BDNF), a growth factor that induces neuronal survival, maturation, and increased electrical activity. In particular, injectable biomaterials comprising BDNF mimetic PAs are provided, as well as methods of using BDNF mimetic PAs for the treatment or prevention of neurological injuries, diseases, and disorders.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121228110
Patent Inventor Names
Alexandra N. Kolberg0
Samuel I. Stupp0
Zaida Alvarez0
Date of Patent
October 22, 2024
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Patent Application Number
170457280
Date Filed
April 5, 2019
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Patent Citations
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US Patent 7371719 Self-assembly of peptide-amphiphile nanofibers under physiological conditions
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US Patent 7390526 Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon
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US Patent 7452679 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
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US Patent 7491690 Self-assembly and mineralization of peptide-amphiphile nanofibers
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US Patent 7534761 Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
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US Patent 7544661 Self-assembling peptide amphiphiles and related methods for growth factor delivery
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US Patent 7554021 Composition and method for self-assembly and mineralization of peptide amphiphiles
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US Patent 7683025 Synthesis and self-assembly of ABC triblock bola peptide amphiphiles
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US Patent 7745708 Self-assembly of peptide-amphiphile nanofibers under physiological conditions
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US Patent 7838491 Self-assembly and mineralization of peptide-amphiphile nanofibers
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US Patent 7851445 Angiogenic heparin-binding epitopes, peptide amphiphiles, self-assembled compositions and related methods of use
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US Patent 8063014 Self-assembly of peptide-amphiphile nanofibers under physiological conditions
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US Patent 8080262 Encapsulated peptide amphiphile nanostructures
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US Patent 8114834 Self-assembling peptide amphiphiles
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US Patent 8114835 Self-assembling peptide amphiphiles for tissue engineering
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US Patent 8124583 Composition and method for self-assembly and mineralization of peptide-amphiphiles
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US Patent 8138140 Self-assembling peptide amphiphiles and related methods for growth factor delivery
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US Patent 8450271 Peptide-based scaffolds for cartilage regeneration and methods for their use
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US Patent 8512693 Self-assembling membranes and related methods thereof
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US Patent 6890654 Encapsulation of nanotubes via self-assembled nanostructures
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Patent Primary Examiner
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Sergio Coffa
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