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US Patent 8063014 Self-assembly of peptide-amphiphile nanofibers under physiological conditions

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Samuel I. Stupp0

Elia Beniash0

Jeffrey D. Hartgerink0

Date of Patent

November 22, 2011

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Patent Application Number

127975860

Date Filed

June 9, 2010

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Patent Citations Received

US Patent 12122811 BDNF mimetic peptide amphiphiles

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US Patent 11964000 Cancer treatment methods using nanofiber stabilized growth factors

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US Patent 11998589 PEGylated peptide amphiphile nanofibers and methods of use

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US Patent 12077795 Method for biocatalytic protein-oligonucleotide conjugation

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US Patent 12116461 Host-guest interactions for pa superstructure formation

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Patent Primary Examiner

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Patent abstract

The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micellar nanofiber composed of beta-sheets, which promote neuron growth and development.

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