US Patent 12103954 Heterodimeric Fc cytokines and uses thereof
Patent 12103954 was granted and assigned to Synthekine on October, 2024 by the United States Patent and Trademark Office.
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US Patent 12103954 Heterodimeric Fc cytokines and uses thereof
Article
Patent abstract
The present disclosure provides IL12 and IL23 muteins as partial agonists comprising modified human p40 molecules that associate with human p35 (hP35) and human P19 (hP19) to form modified hIL-12 and IL23 partial agonists wherein the individual components of IL12 and IL23 muteins are linked to engineered Fc domains.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Deepti Rokkam0
Patrick Lupardus0
Date of Patent
October 1, 2024
0Patent Application Number
185821800
Date Filed
February 20, 2024
0Patent Citations
Patent Primary Examiner
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