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US Patent 11358999 IL-12 heterodimeric Fc-fusion proteins

Patent 11358999 was granted and assigned to Xencor on June, 2022 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Rajat Varma0

Nargess Hassanzadeh-Kiabi0

Matthew Bernett0

Ke Liu0

John R. Desjarlais0

Rumana Rashid0

Date of Patent

June 14, 2022

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Patent Application Number

165926560

Date Filed

October 3, 2019

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Patent Citations

US Patent 10696722 Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same

Patent Citations Received

US Patent 12103954 Heterodimeric Fc cytokines and uses thereof

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US Patent 11851466 Targeted IL-12 heterodimeric Fc-fusion proteins

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US Patent 11866476 Masked IL-2-Fc fusion polypeptides

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US Patent 11655277 IL-12 heterodimeric Fc-fusion proteins

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Patent Primary Examiner

Zachary C Howard

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CPC Code

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The present invention provides novel IL-12 Fc fusion proteins, methods of making and using the same. The IL-12. Fc fusion proteins are useful for treatment of cancer and can be used in combination with checkpoint blockade.

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