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US Patent 12091397 Dihydroquinolinones for medical treatment

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Patent attributes

Patent Applicant

C4 Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Annick Goergler0

Eric Andre Kusznir0

Fabian Dey0

Moreno Attilio Wichert0

Roger Norcross0

Adrian Britschgi0

Date of Patent

September 17, 2024

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Patent Application Number

178787530

Date Filed

August 1, 2022

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Patent Citations

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US Patent 11254672 Dihydrobenzimidazolones for medical treatment

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US Patent 11401256 Dihydroquinolinones for medical treatment

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...

Patent Primary Examiner

Medhanit W Bahta

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Patent abstract

The present invention provides dihydroquinolinone compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. The disclosed compounds are useful for the treatment of cancer.

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