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US Patent 12060575 Methods of expanding embryonic stem cells in a suspension culture

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Joseph Itskovitz-Eldor0

Michal Amit0

Date of Patent

August 13, 2024

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Patent Application Number

171782790

Date Filed

February 18, 2021

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Patent Citations

US Patent 10968427 Methods of expanding embryonic stem cells in a suspension culture

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US Patent 9834749 Methods of expanding embryonic stem cells in a suspension culture

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US Patent 10385312 Media for culturing stem cells

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US Patent 7250294 Screening small molecule drugs using neural cells differentiated from human embryonic stem cells

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US Patent 7413902 Feeder-free culture method for embryonic stem cells or primate primordial stem cells

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US Patent 7413904 Human embryonic stem cells having genetic modifications

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US Patent 7432104 Methods for the culture of human embryonic stem cells on human feeder cells

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US Patent 7452718 Direct differentiation method for making cardiomyocytes from human embryonic stem cells

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Patent Primary Examiner

Arthur S Leonard

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Patent abstract

A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.

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