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US Patent 12024750 Methylation markers and targeted methylation probe panel

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 US Patent 12024750 Methylation markers and targeted methylation probe panel

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Patent abstract

The present description provides a cancer assay panel for targeted detection of cancer-specific methylation patterns. Further provided herein includes methods of designing, making, and using the cancer assay panel for diagnosis of cancer.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120247500
Patent Inventor Names
Alexander P. Fields0
Arash Jamshidi0
Hamed Amini0
M. Cyrus Maher0
Oliver Claude Venn0
Rongsu Qi0
Samuel S. Gross0
Seyedmehdi Shojaee0
Srinka Ghosh0
Date of Patent
July 2, 2024
0
Patent Application Number
170610480
Date Filed
October 1, 2020
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Patent Citations
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US Patent 7371526 Method and materials for bisulfite conversion of cytosine to uracil
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US Patent 7700282 Method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids
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US Patent 7700324 Methylated CpG island amplification (MCA)
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US Patent 7749702 Methods and nucleic acids for the analyses of cellular proliferative disorders
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US Patent 8137937 Method for bisulfite treatment
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US Patent 9862995 Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
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US Patent 9868756 Method for bisulfite treatment
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US Patent 9896725 Real-time, label-free detection of macromolecules in droplets based on electrical measurements
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US Patent 9896726 Methods and compositions for discrimination between cytosine and modifications thereof, and for methylome analysis
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US Patent 9902992 Systems and methods to detect rare mutations and copy number variation
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US Patent 9920363 Constructing method of high-throughput sequencing library and use thereof
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US Patent 9920366 Methods and systems for detecting genetic variants
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US Patent 9984201 Method and system for determining cancer status
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US Patent 10011878 Compositions and methods for performing methylation detection assays
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US Patent 10031131 Selective oxidation of 5-methylcytosine by TET-family proteins
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US Patent 10093986 Leukemia methylation markers and uses thereof
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US Patent 10297342 Classification of cancer level based on genomic coordinates of outermost nucleotides of cell-free DNA
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US Patent 10718026 Methylation assay
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US Patent 7041455 Method and apparatus for pattern identification in diploid DNA sequence data
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Patent Primary Examiner
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Robert T. Crow
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