US Patent 11939365 T cell receptors recognizing mutated P53
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US Patent 11939365 T cell receptors recognizing mutated P53
Article
Patent abstract
Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Infobox
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Patent Jurisdiction
Patent Number
Patent Inventor Names
Anna Pasetto0
Drew C. Deniger0
Maria R. Parkhurst0
Parisa Malekzadeh0
Paul F. Robbins0
Rami Yoseph0
Steven A. Rosenberg0
Winifred M. Lo0
Yong-Chen Lu0
Date of Patent
March 26, 2024
0Patent Application Number
166512420
Date Filed
September 17, 2018
0Patent Citations
Patent Primary Examiner
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